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Optometry Board Practice Test for the NBEO® Part 1 Test #1 – Biochemistry This test is comprised of 6 items, which must be completed within 6 minutes. |
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What molecule acts as a reducing agent in the protection against superoxide?
B. NADPH. These agents are found along the sorbitol pathway. This pathway is important in understanding the breakdown of glucose in the body. One molecule of glucose can either undergo reduction to sorbitol in a low oxygen environment or can be converted directly to fructose 6-phosphate.
B. NADPH. These agents are found along the sorbitol pathway. This pathway is important in understanding the breakdown of glucose in the body. One molecule of glucose can either undergo reduction to sorbitol in a low oxygen environment or can be converted directly to fructose 6-phosphate.
Which of the following is a feedback regulator of synthesis and secretion of glucocorticoids?
A. ACTH (adrenocorticotropic hormone). ACTH secretion is diurnal and regulated by corticotropin releasing hormone. This secretion is increased during stress and highest in the morning.
A. ACTH (adrenocorticotropic hormone). ACTH secretion is diurnal and regulated by corticotropin releasing hormone. This secretion is increased during stress and highest in the morning.
Which amino acid is found in the first step in production of epinephrine?
D. Epinephrine is derived from Tyrosine. Tyrosine molecules are converted to dopamine which leads to production and release of norepinephrine. Norepinephrine is converted to epinephrine via methyltransferase.
D. Epinephrine is derived from Tyrosine. Tyrosine molecules are converted to dopamine which leads to production and release of norepinephrine. Norepinephrine is converted to epinephrine via methyltransferase.
Serotonin, a neurotransmitter, is synthesized using which amino acid?
C. Tryptophan is the sole precursor for the synthesis of serotonin. We acquire this amino acid through our diet only.
C. Tryptophan is the sole precursor for the synthesis of serotonin. We acquire this amino acid through our diet only.
What changes to Vmax and the Lineweaver-Burk Plot would you expect when a ligand binds to an allosteric site on the same target molecule as the substrate?
C. In this example of non-competitive inhibition, one would expect Vmax to decrease, Km to remain constant, and the Lineweaver-Burk plot to shift upwards. In competitive inhibition, the ligand will bind to the active site in place of the substrate. This will cause Vmax to remain constant, Km to increase, and the plot to shift to the right.
C. In this example of non-competitive inhibition, one would expect Vmax to decrease, Km to remain constant, and the Lineweaver-Burk plot to shift upwards. In competitive inhibition, the ligand will bind to the active site in place of the substrate. This will cause Vmax to remain constant, Km to increase, and the plot to shift to the right.
Which of the following vitamins is NOT soluble in fat?
E. Vitamin C is soluble in water. To recall, “DEAK” are the four fat soluble vitamins.
E. Vitamin C is soluble in water. To recall, “DEAK” are the four fat soluble vitamins.